This module defines data structures for Aliev-Panfilov cellular activation model for cardiac electrophysiology. More...

#include <CepModAp.h>

Public Member Functions
	CepModAp ()

void	actv_strs (const double X, const double dt, double &Tact, double &epsX)
	Compute activation force for electromechanics based on active stress model. More...

void	getf (const int n, const Vector< double > &X, Vector< double > &f, const double fext)

void	getj (const int n, const Vector< double > &X, Array< double > &Jac, const double Ksac)

void	init (const int nX, Vector< double > &X)
	SUBROUTINE AP_INIT0(nX, X) More...

void	init (const int nX, Vector< double > &X, double X0)
	SUBROUTINE AP_INITS(nX, X, X0) More...

void	init (const int nX, Vector< double > &X, Vector< double > &X0)
	SUBROUTINE AP_INITV(nX, X, X0) More...

void	integ_cn2 (const int nX, Vector< double > &Xn, const double Ts, const double Ti, const double Istim, const double Ksac, Vector< int > &IPAR, Vector< double > &RPAR)
	Time integration performed using Crank-Nicholson method. More...

void	integ_fe (const int nX, Vector< double > &X, const double Ts, const double Ti, const double Istim, const double Ksac)
	Time integration performed using Forward Euler method. More...

void	integ_rk (const int nX, Vector< double > &X, const double Ts, const double Ti, const double Istim, const double Ksac)
	Time integration performed using 4th order Runge-Kutta method. More...

Public Attributes
double	Vscale = 100.0
	Voltage scaling. More...

double	Tscale = 12.90
	Time scaling. More...

double	Voffset = -80.0
	Voltage offset parameter. More...

double	alpha = 1.E-2
	Model parameters. More...

double	a = 2.E-3

double	b = 0.150

double	c = 8.0

double	mu1 = 0.20

double	mu2 = 0.30

double	Vrest = -80.0
	Resting voltage (mV) More...

double	Vcrit = -30.0
	Critical voltage (mV) More...

double	eta_T = 5.E-3
	Saturation potential. More...

double	eps_0 = 0.10
	Minimum activation (ms^{-1}) More...

double	eps_i = 1.0
	Maximum activation (ms^{-1}) More...

double	xi_T = 1.0
	Transition rate (mV^{-1}) More...

double	Cm = 1.0
	Cm: Cell capacitance per unit surface area. More...

double	sV = 1.0
	sV: Surface to volume ratio More...

double	rho = 1.0
	rho: Cellular resistivity More...

Detailed Description

This module defines data structures for Aliev-Panfilov cellular activation model for cardiac electrophysiology.

Copyright (c) Stanford University, The Regents of the University of California, and others.

See Copyright-SimVascular.txt for additional details.

Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions:

The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software.

THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT OWNER OR CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.

The classes defined here duplicate the data structures in the Fortran APMOD module defined in CEPMOD_AP.f and PARAMS_AP.f files.

Constructor & Destructor Documentation

◆ CepModAp()

CepModAp::CepModAp ( )

Copyright (c) Stanford University, The Regents of the University of California, and others.

See Copyright-SimVascular.txt for additional details.

Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions:

The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software.

THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT OWNER OR CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.

Member Function Documentation

◆ actv_strs()

void CepModAp::actv_strs	(	const double	X,
		const double	dt,
		double &	Tact,
		double &	epsX
	)

Compute activation force for electromechanics based on active stress model.

Replicates 'SUBROUTINE AP_ACTVSTRS(X, dt, Tact, epsX)' defined in 'CEPMOD_AP.f'.

◆ init() [1/3]

void CepModAp::init	(	const int	nX,
		Vector< double > &	X
	)

SUBROUTINE AP_INIT0(nX, X)

◆ init() [2/3]

void CepModAp::init	(	const int	nX,
		Vector< double > &	X,
		double	X0
	)

SUBROUTINE AP_INITS(nX, X, X0)

◆ init() [3/3]

void CepModAp::init	(	const int	nX,
		Vector< double > &	X,
		Vector< double > &	X0
	)

SUBROUTINE AP_INITV(nX, X, X0)

◆ integ_cn2()

void CepModAp::integ_cn2	(	const int	nX,
		Vector< double > &	Xn,
		const double	Ts,
		const double	Ti,
		const double	Istim,
		const double	Ksac,
		Vector< int > &	IPAR,
		Vector< double > &	RPAR
	)

Time integration performed using Crank-Nicholson method.

Replicates 'SUBROUTINE AP_INTEGCN2(nX, Xn, Ts, Ti, Istim, Ksac, IPAR, RPAR)' defined in 'CEPMOD_AP.f'.

◆ integ_fe()

void CepModAp::integ_fe	(	const int	nX,
		Vector< double > &	X,
		const double	Ts,
		const double	Ti,
		const double	Istim,
		const double	Ksac
	)

Time integration performed using Forward Euler method.

Replicates 'SUBROUTINE AP_INTEGFE(nX, X, Ts, Ti, Istim, Ksac)' defined in 'CEPMOD_AP.f'.

◆ integ_rk()

void CepModAp::integ_rk	(	const int	nX,
		Vector< double > &	X,
		const double	Ts,
		const double	Ti,
		const double	Istim,
		const double	Ksac
	)

Time integration performed using 4th order Runge-Kutta method.

Replicates 'SUBROUTINE AP_INTEGRK(nX, X, Ts, Ti, Istim, Ksac)' defined in 'CEPMOD_AP.f'.

Member Data Documentation

◆ alpha

double CepModAp::alpha = 1.E-2

Model parameters.

◆ Cm

double CepModAp::Cm = 1.0

Cm: Cell capacitance per unit surface area.

◆ eps_0

double CepModAp::eps_0 = 0.10

Minimum activation (ms^{-1})

◆ eps_i

double CepModAp::eps_i = 1.0

Maximum activation (ms^{-1})

◆ eta_T

double CepModAp::eta_T = 5.E-3

Saturation potential.

◆ rho

double CepModAp::rho = 1.0

rho: Cellular resistivity

◆ sV

double CepModAp::sV = 1.0

sV: Surface to volume ratio

◆ Tscale

double CepModAp::Tscale = 12.90

Time scaling.

◆ Vcrit

double CepModAp::Vcrit = -30.0

Critical voltage (mV)

◆ Voffset

double CepModAp::Voffset = -80.0

Voltage offset parameter.

◆ Vrest

double CepModAp::Vrest = -80.0

Resting voltage (mV)

◆ Vscale

double CepModAp::Vscale = 100.0

Voltage scaling.

◆ xi_T

double CepModAp::xi_T = 1.0

Transition rate (mV^{-1})

The documentation for this class was generated from the following files:

svFSI/CepModAp.h
svFSI/CepModAp.cpp

Public Member Functions

Public Attributes